Latest posts · Page 2085

@bluemoondance74 @StephenKing Cold symptoms are gone for now 😀🚀💫

@StephenKing There are degrees of pos

@MrSammy_H @pelagicbird @max_roi @rossy65 Heneghan makes a lot of sense. Hilarious that he has to clarify that he runs the Center for *Evidence-Based* Medicine at Oxford 🤣🤣. General public doesn’t realize quite how much of medicine is subjective or outright witchcraft.

@WhatsupFranks The number of PCR amplification cycles required to detect the virus is a rough indicator of your viral load. From what I can gather, you’re probably not infectious above 30 & you probably are below 25. Sound about right?

@MrSammy_H @max_roi @rossy65 This a great reference! Worth a read.

Case closed https://t.co/pUYiJcAdD6

Soon https://t.co/mWOpR7W8kk

@PPathole Fwiw, lab I just spoke to thinks below 30 is accurate, 30 to 40 gets dicey & above 40 is bs. Will talk to several more labs. There must be a graph of PCR amplification cycle vs false positive rate somewhere.

Lab I just spoke to said cov2 PCR detection (N1 & N3 genes) below 30 cycles is reliable & above 40 cycles is not

@RationalEtienne @ryaneshea Note, this is not the spike protein. They don’t consider that reliable.

@RationalEtienne @ryaneshea Just spoke directly to a testing lab. Their main PCR search is for the N1 gene, unique to cov2. N3 is also sought, but is generic to other sars viruses. High PCR cycle count *does* give false positives, but they believe accuracy is good below 30 cycles & 40 cycles is their max.

@PPathole Strange

@ryaneshea Possible explanation for the dramatic decline in cold & flu prevalence vs prior years. If someone comes in with cold/flu symptoms & falsely tests positive for cov2, they will assume they have it, when in fact they simply have some other form of seasonal cold/flu.

@ryaneshea Moreover, lower the true prevalence, the higher the false positive number will be. This sounds obvious, but it could mean a very high false positive percentage if true prevalence is low.

@ryaneshea From https://t.co/42z7vRPB9c https://t.co/XTSukcc3Tl

@dana_e_morgan Sure is

Would be great to hear from people who know a lot about the PCR testing industry. What’s the approximate false positive rate, all things considered, for cov2 PCR tests?

@ClareCraigPath Interesting

@john_beans @DirtyTesla Interesting

What is the general population (no knowledge of symptoms) accuracy of a sars-cov2 PCR test & is it possible to generate a false positive if you simply run enough cycles?